Genetics and Aging in Protozoa

摘要: Publisher Summary This chapter discusses the genetics of aging in protozoa. Protozoa can exhibit a finite growth potential and escape extinction by fertilization formation successive generations. Aging ciliates exhibits predictable, progressive, species-specific rates decline function and, finally, death. In absence fertilization, cells undergo repeated cell divisions produce that are progressively less vigorous than progenitor cell. Fertilization represents risk result immediate death, reduced life span, or resetting age clock to zero. The outcome process is dependent on breeding behavior, individuals participating cross, their ages. present an untapped reservoir for evolutionary approach identification fundamental mechanisms utilized assurance longevity. Similarities between age-associated changes protozoa multicellular organisms discussed, similarities among unicells multicells described. Molecular direct determinations gene emerging rapidly. presence repressors derepressors cytoplasmic environment developing nucleus turn off certain genes, once activated repressed, perpetuate state.