BIOMEDICINE: A Sympathetic Defense Against Obesity

作者: A. G. Dulloo

DOI: 10.1126/SCIENCE.1074923

关键词:

摘要: One of the most puzzling questions in obesity research is why some humans rapidly gain weight when they overeat, whereas others do not. In a compelling Perspective, [Dulloo][1] explains exciting new findings ([ Bachman et al .][2]) that reveal molecular mechanisms underlying thermogenesis, process which extra food converted into heat instead fat. As Dulloo discloses, diet-induced thermogenesis under control signaling through b-adrenergic receptors sympathetic nervous system. This work opens door to developing anti-obesity therapeutics activate thermogenesis. [1]: http://www.sciencemag.org/cgi/content/full/297/5582/780 [2]: http://www.sciencemag.org/cgi/content/full/297/5582/843

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