Modeling the Implementation of Universal Coverage for HIV Treatment as Prevention and its Impact on the HIV Epidemic

摘要: The Joint United Nations Programme on HIV/AIDS (UNAIDS) recently updated its global targets for antiretroviral therapy (ART) coverage HIV-positive persons under which 90 % of people are tested, those ART, and achieve viral suppression. Treatment policy is moving toward treating all HIV-infected regardless CD4 cell count-otherwise known as treatment prevention-in order to realize the full therapeutic preventive benefits ART. Mathematical models have played an important role in guiding development these policies by projecting long-term health impacts cost-effectiveness. To guide future policy, new mathematical must consider barriers patients face receiving taking Here, we describe HIV care cascade ART delivery supply chain examine how modeling can provide insight into cost-effective strategies scaling-up sub-Saharan Africa help universal coverage.