A novel magnetic resonance imaging approach to collateral flow imaging in ischemic stroke.

摘要: Objective Dedicated magnetic resonance (MR) imaging (MRI) sequences for evaluation of collaterals can be generated using MR perfusion (MRP) source data. We compared a novel collateral flow technique with digital subtraction angiography (DSA) determining circulation in acute stroke and evaluated the ability MR-based maps to predict outcomes after recanalization therapy. Methods Consecutive patients who were candidates endovascular treatment enrolled. A map derived from MRP data was by manual or automatic postprocessing. Collateral grading based on performed DSA. Clinical radiological according early reperfusion (ER) status. Results There good correlation between MRI-based DSA-based grades (weighted κ-coefficient = 0.70). status achievement ER 2 main determinants favorable functional outcome neurological improvement, addition infarct growth. Regardless ER, better significantly associated lower modified Rankin score at day 90 (p < 0.001 trend both ER− ER+). Most symptomatic intracranial hemorrhages occurred poor grade ER+, whereas no patient excellent suffered hemorrhage died. Interpretation MRI techniques assess are rapidly being developed, may provide insight into perfusion. The combination images pretreatment is robust predictor ischemic stroke. Ann Neurol 2014;76:356–369