Selective hdac3 inhibitors

作者: John H. Van Duzer , Ralph Mazitschek

DOI:

关键词:

摘要: Provided herein are HDAC3 inhibitors, as well methods of treatment comprising administering these compounds to a subject in need thereof.

参考文章(25)
Jean Jacques, André Collet, Samuel H. Wilen, Enantiomers, Racemates, and Resolutions ,(1981)
David J. Witter, Matthew G. Stanton, David L. Sloman, Kevin J. Wilson, Thomas A. Miller, Fluorinated Arylamide Derivatives ,(2007)
Peeyush K. Lala, Amila Orucevic, Role of nitric oxide in tumor progression: Lessons from experimental tumors Cancer and Metastasis Reviews. ,vol. 17, pp. 91- 106 ,(1998) , 10.1023/A:1005960822365
Peter G. M. Wuts, Theodora W. Greene, Protective groups in organic synthesis ,(1981)
Alfonso R. Gennaro, Joseph P. Remington, Remington's pharmaceutical sciences Published in <b>1975</b> in Easton Pa) by Mack. ,(1985)
Achim Kless, Gregor Bahrenberg, Sven Kühnert, Wolfgang Schröder, Substituted 2-mercaptoquinoline-3-carboxamides as KCNQ2/3 modulators ,(2010)
Junichi Ishikawa, Koichi Saito, Norihisa Ohe, Kentaro Kobayashi, Agent for treatment or prevention of diseases associated with activity of neurotrophic factors ,(2010)
M. A. Lazar, M. A. Wood, S. C. McQuown, R. M. Barrett, D. P. Matheos, R. J. Post, G. A. Rogge, T. Alenghat, S. E. Mullican, S. Jones, J. R. Rusche, HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation The Journal of Neuroscience. ,vol. 31, pp. 764- 774 ,(2011) , 10.1523/JNEUROSCI.5052-10.2011
Alan P. Kozikowski, Yufeng Chen, Arsen Gaysin, Bin Chen, Melissa A. D'Annibale, Carla M. Suto, Brett C. Langley, Functional differences in epigenetic modulators-superiority of mercaptoacetamide-based histone deacetylase inhibitors relative to hydroxamates in cortical neuron neuroprotection studies. Journal of Medicinal Chemistry. ,vol. 50, pp. 3054- 3061 ,(2007) , 10.1021/JM070178X
Maria M. Mihaylova, Debbie S. Vasquez, Kim Ravnskjaer, Pierre-Damien Denechaud, Ruth T. Yu, Jacqueline G. Alvarez, Michael Downes, Ronald M. Evans, Marc Montminy, Reuben J. Shaw, Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis. Cell. ,vol. 145, pp. 607- 621 ,(2011) , 10.1016/J.CELL.2011.03.043