Mechanisms and results of balloon angioplasty for the treatment of in-stent restenosis.

摘要: Restenosis within tubular slotted stents is secondary to intimal hyperplasia and usually treated with percutaneous transluminal coronary angioplasty (PTCA). Sequential intravascular ultrasound (IVUS) was used assess the mechanisms results of PTCA for in-stent restenosis. Sixty-four restenotic Palmaz-Schatz were studied by IVUS imaging before after PTCA. measurements stent lumen cross-sectional areas (CSAs) at 5 segments (proximal distal edges, proximal bodies, central articulation) calculate CSA (stent — CSA). The then averaged. Mean minimum CSAs compared Quantitative angiographic showed a minimal diameter increase from 1.05 ± 0.63 mm (mean 1 SD) intervention 2.77 0.51 (p <0.0001). Conversely, stenosis decreased 63 19% 18 12% 2.3 1.3 mm2 6.1 2.2 <0.0001) as result an increased (7.2 2.4 8.7 2.6 mm2, p (4.9 2.7 2.0 Of total mean enlargement, 56 28% additional expansion 44 decrease in neointimal tissue. significantly smaller than (presumably accurate reflection dimensions immediately implantation; = 0.0002). mechanism restenosis combination tissue extrusion out stent; there relatively high residual (angiographic 12%). (Am J Cardiol 1996;78:618–622)