Effect on postoperative sore throat of spraying the endotracheal tube cuff with benzydamine hydrochloride, 10% lidocaine, and 2% lidocaine.
作者： Nan-Kai Hung , Ching-Tang Wu , Shun-Ming Chan , Chueng-He Lu , Yuan-Shiou Huang
DOI: 10.1213/ANE.0B013E3181D4854E
关键词:
摘要: BACKGROUND: Postoperative sore throat (POST) is a common complication after endotracheal intubation. We compared the effectiveness on POST of spraying tube (ETT) cuff with benzydamine hydrochloride, 10% lidocaine, and 2% lidocaine. METHODS: Three hundred seventy-two patients were randomly allocated into 4 groups. The ETT cuffs in each group sprayed lidocaine or normal saline before After insertion, inflated to an airway leak pressure 20 cm H 2 0. Anesthesia was maintained propofol. examined for (none, mild, moderate, severe) at 1, 6, 12, 24 hours extubation. RESULTS: highest incidence occurred 6 extubation all There significantly lower than groups (P < 0.05) observation time point. At extubation, (17.0%) (53.7%), (37.0%), (40.8%) 0.05). had decreased severity Compared groups, increased 12 no significant differences among local systemic side effects. CONCLUSIONS: Spraying hydrochloride simple effective method reduce POST.
sci-hub.se 参考文章(27)
Turnbull Rs, Benzydamine Hydrochloride (Tantum) in the management of oral inflammatory conditions. Journal of The Canadian Dental Association. ,vol. 61, pp. 127- 134 ,(1995)
Joel B. Epstein, Sol Silverman, Dario A. Paggiarino, Steve Crockett, Mark M. Schubert, Neil N. Senzer, Peter B. Lockhart, Michael J. Gallagher, Douglas E. Peterson, Francis G. Leveque, Benzydamine HCl for prophylaxis of radiation‐induced oral mucositis Cancer. ,vol. 92, pp. 875- 885 ,(2001) , 10.1002/1097-0142(20010815)92:4<875::AID-CNCR1396>3.0.CO;2-1
N. K. Schønemann, M. Burght, L. Arendt-Nielsen, P. Bjerring, Onset and duration of hypoalgesia of lidocaine spray applied to oral mucosa--a dose response study. Acta Anaesthesiologica Scandinavica. ,vol. 36, pp. 733- 735 ,(1992) , 10.1111/J.1399-6576.1992.TB03554.X
M. EL Hakim, Beclomethasone prevents postoperative sore throat. Acta Anaesthesiologica Scandinavica. ,vol. 37, pp. 250- 252 ,(1993) , 10.1111/J.1399-6576.1993.TB03709.X
D Passàli, Efficacy and safety of ketoprofen lysine salt mouthwash versus benzydamine hydrochloride mouthwash in acute pharyngeal inflammation: a randomized, single-blind study. Clinical Therapeutics. ,vol. 23, pp. 1508- 1518 ,(2001) , 10.1016/S0149-2918(01)80123-5
Alex Macario, Matthew Weinger, Stacie Carney, Ann Kim, Which Clinical Anesthesia Outcomes Are Important to Avoid? The Perspective of Patients Anesthesia & Analgesia. ,vol. 89, pp. 652- 658 ,(1999) , 10.1097/00000539-199909000-00022
P. Biro, B. Seifert, T. Pasch, Complaints of sore throat after tracheal intubation European Journal of Anaesthesiology. ,vol. 22, pp. 307- 311 ,(2005) , 10.1017/S0265021505000529
Mark C. Monroe, Nikolaus Gravenstein, Segundina Saga-Rumley, Postoperative sore throat: effect of oropharyngeal airway in orotracheally intubated patients. Anesthesia & Analgesia. ,vol. 70, pp. 512- 516 ,(1990) , 10.1213/00000539-199005000-00008
Thomas Modéer, Tülay Yucel-Lindberg, Benzydamine reduces prostaglandin production in human gingival fibroblasts challenged with interleukin-1β or tumor necrosis factor a Acta Odontologica Scandinavica. ,vol. 57, pp. 40- 45 ,(1999) , 10.1080/000163599429093
Koichi Maruyama, Hironori Sakai, Hideki Miyazawa, Kyou Iijima, Naoyuki Toda, Shuji Kawahara, Katsumi Hara, Laryngotracheal application of lidocaine spray increases the incidence of postoperative sore throat after total intravenous anesthesia. Journal of Anesthesia. ,vol. 18, pp. 237- 240 ,(2004) , 10.1007/S00540-004-0264-2