Patterns of operative mortality following esophagectomy.

作者: C. Schieman , D. A. Wigle , C. Deschamps , F. C. Nichols III , S. D. Cassivi

DOI: 10.1111/J.1442-2050.2011.01304.X

关键词:

摘要: SUMMARY Esophagectomy has one of the highest mortality rates among all surgical procedures. We investigated type and frequency complications associated with perioperative after esophagectomy. performed a retrospective review deaths following esophagectomy for esophageal cancer at Mayo Clinic, Rochester from 1993 through 2009. Of 1522 esophagectomies, occurred in 45 (3.0%). The majority who died were male (82%); median age was 72 years (range 46–92). age-adjusted Charlson comorbidity score 6. Twenty-three (51%) underwent neoadjuvant chemoradiotherapy. transthoracic 27 patients (60%), transhiatal eight (18%), tri-incisional seven (16%), left thoracoabdominal (2%), transabdominal (2%). A mean 3.2 major prior to death (median 2.5, range 1–8), most common being pulmonary occurring 30 (67%) anastomotic 20 (44%). primary underlying cause 18 (40%) each, respectively, abdominal sepsis three (7%), fatal hemorrhage embolism, stroke multisystem organ failure each respectively. Patients 19 days 3–98) Most experienced multiple serious rather than single causative event. Major implicated vast mortality, should remain focus efforts improve clinical outcomes.

参考文章(34)
A. M. Gillinov, R. F. Heitmiller, Strategies to reduce pulmonary complications after transhiatal esophagectomy Diseases of The Esophagus. ,vol. 11, pp. 43- 47 ,(1998) , 10.1093/DOTE/11.1.43
Sandra Tomaszek, Stephen D. Cassivi, Esophagectomy for the treatment of esophageal cancer. Gastroenterology Clinics of North America. ,vol. 38, pp. 169- 181 ,(2009) , 10.1016/J.GTC.2009.01.010
Stephen D Cassivi, Leaks, strictures, and necrosis: a review of anastomotic complications following esophagectomy Seminars in Thoracic and Cardiovascular Surgery. ,vol. 16, pp. 124- 132 ,(2004) , 10.1053/J.SEMTCVS.2004.03.011
Jan B.F Hulscher, Jan G.P Tijssen, Hugo Obertop, J.Jan B van Lanschot, Transthoracic versus transhiatal resection for carcinoma of the esophagus: a meta-analysis The Annals of Thoracic Surgery. ,vol. 72, pp. 306- 313 ,(2001) , 10.1016/S0003-4975(00)02570-4
Mary E. Charlson, Peter Pompei, Kathy L. Ales, C.Ronald MacKenzie, A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation☆ Journal of Chronic Diseases. ,vol. 40, pp. 373- 383 ,(1987) , 10.1016/0021-9681(87)90171-8
J. M. Müller, H. Erasmi, M. Stelzner, U. Zieren, H. Pichlmaier, Surgical therapy of oesophageal carcinoma. British Journal of Surgery. ,vol. 77, pp. 845- 857 ,(2005) , 10.1002/BJS.1800770804
David Bergqvist, John A. Heit, Michael R. Lassen, Joel C. Ray, Willitim Geerts, Graham F. Pineo, Clifford W. Colwell, Prevention of Venous Thromboembolism ,(1994)
Rik Gosselink, Katleen Schrever, Philippe Cops, Hilde Witvrouwen, Paul De Leyn, Thierry Troosters, Antoon Lerut, Georges Deneffe, Marc Decramer, Incentive spirometry does not enhance recovery after thoracic surgery. Critical Care Medicine. ,vol. 28, pp. 679- 683 ,(2000) , 10.1097/00003246-200003000-00013
Giuseppe Portale, Jeffrey A. Hagen, Jeffrey H. Peters, Linda S. Chan, Steven R. DeMeester, Tasha A.K. Gandamihardja, Tom R. DeMeester, Modern 5-year survival of resectable esophageal adenocarcinoma: single institution experience with 263 patients. Journal of The American College of Surgeons. ,vol. 202, pp. 588- 596 ,(2006) , 10.1016/J.JAMCOLLSURG.2005.12.022