作者: C. Schieman , D. A. Wigle , C. Deschamps , F. C. Nichols III , S. D. Cassivi
DOI: 10.1111/J.1442-2050.2011.01304.X
关键词:
摘要: SUMMARY Esophagectomy has one of the highest mortality rates among all surgical procedures. We investigated type and frequency complications associated with perioperative after esophagectomy. performed a retrospective review deaths following esophagectomy for esophageal cancer at Mayo Clinic, Rochester from 1993 through 2009. Of 1522 esophagectomies, occurred in 45 (3.0%). The majority who died were male (82%); median age was 72 years (range 46–92). age-adjusted Charlson comorbidity score 6. Twenty-three (51%) underwent neoadjuvant chemoradiotherapy. transthoracic 27 patients (60%), transhiatal eight (18%), tri-incisional seven (16%), left thoracoabdominal (2%), transabdominal (2%). A mean 3.2 major prior to death (median 2.5, range 1–8), most common being pulmonary occurring 30 (67%) anastomotic 20 (44%). primary underlying cause 18 (40%) each, respectively, abdominal sepsis three (7%), fatal hemorrhage embolism, stroke multisystem organ failure each respectively. Patients 19 days 3–98) Most experienced multiple serious rather than single causative event. Major implicated vast mortality, should remain focus efforts improve clinical outcomes.