System and method for delivering agents into targeted tissue of a living being

摘要: The systems basically comprise a delivery system for accessing the targeted tissue within living being and introduction of at least one agent select locations into myocardium other tissues. are arranged to access tissues heart. One or more can be utilized during transluminal, transthoracic direct surgical procedures. Where appropriate, example in case intraventricular access, portions steerable properly orient device. instruments may pierce heart create channels extending from endocardium, epicardium, cardiac vessels. When penetration is utilized, device include feature control depth penetration. To minimize bleeding through dilate small initial punctures that later contract down after removal. formation required, this achieved, by way example, with rotary-tipped device, pressurized fluid jet devices, vibratory piercing needle-like tip devices. utilize some form mechanical action application energy (e.g. electrical, sonic, thermal, optical, fluid, radio frequency (RF), nuclear) process. affect surrounding distance delivered pharmaceuticals, biologically active agents, radiopaque materials, etc.