58. Cortical sources of resting state EEG rhythms in Alzheimer’s disease patients are related to the integrity of structural brain connectivity as revealed by tractography: An EEG-DTI combined study

摘要: Alzheimer’s disease (AD) patients show abnormal cortical sources of resting state EEG rhythms, especially at delta (1–4 Hz) and alpha (8–13 Hz) bands. Here we hypothesized that this abnormality is correlated to impaired structural brain connectivity. Eyes closed MRI-DTI (diffusion tensor imaging) data were acquired in 21 AD 9 mild cognitive impairment (MCI) patients. LORETA FSL used for analysis. Compared MCI subjects, showed a reduction DTI fractional anisotropy (FA) several white matter bundles ( p