One-pot biotransformation of glycerol into serinol catalysed by biocatalytic composites made of whole cells and immobilised enzymes
作者： Fernando López-Gallego , Fernando López-Gallego , Eleftheria Diamanti , Susana Velasco-Lozano , Erienne Jackson
DOI: 10.1039/D0GC03918G
关键词:
摘要: Biocatalytic cascades afford the development of economically sustainable and green processes. Herein we examined unprecedented coupling co-immobilised Gluconobacter oxydans an isolated transaminase to synthesise serinol from glycerol. Through this approach, manufactured up 36 mM serinol, highest titer ever reported for a non-fermentative biosynthesis. More importantly, similar productivities are obtained starting industrial by-product crude glycerol, demonstrating possibilities hybrid heterogenenous biocatalyst valorising bio-based raw materials.
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