Radiotherapy for primary localized (stage I and II) non-Hodgkin's lymphoma of the oral cavity.

作者: Kohji Sunaba , Hitoshi Shibuya , Norihiko Okada , Teruo Amagasa , Shoji Enomoto

DOI: 10.1016/S0360-3016(00)00412-0

关键词:

摘要: Abstract Purpose: To assess the role of radiation therapy in treatment primary localized (Stage I: 24 cases and Stage II: 13 cases) non-Hodgkin’s Lymphoma (NHL) oral cavity. Methods Materials: In total, 37 patients (27 male, 10 female) with NHL cavity have been treated radiotherapy alone (23 or chemotherapy (14 cases). The age range was 29 to 86 years (median: 65). Clinical variables potential prognostic significance for survival were evaluated by univariate multivariate analysis. Of patients, 31 (84%) had intermediate-grade lymphomas six (14%) high-grade lymphomas. Four showed necrotic ulcer central portion hard palate. Results: 5-year actuarial rate all 73%. rates lymphoma 85% 14%, respectively. Significant factors identified analysis histologic grade malignancy ( p = 0.02) tumor 0.02). Chemotherapy did not improve 0.41). Conclusions: Our suggests that may be approved as no ulceration intermediate histology. However, and/or are difficult cure aggressive should advocated survival.

参考文章(25)
Henry F. Frierson, Stacey E. Mills, Donald J. Innes, Non-Hodgkin's lymphomas of the sinonasal region: histologic subtypes and their clinicopathologic features. American Journal of Clinical Pathology. ,vol. 81, pp. 721- 727 ,(1984) , 10.1093/AJCP/81.6.721
Mauro Melato, Paolo Pecorari, Non-Hodgkin's lymphoma (NHL) of the oral cavity. Anticancer Research. ,vol. 18, pp. 1299- 1302 ,(1998)
R Otter, WBJ Gerrits, MMVD Sandt, J Hermans, R Willemze, Study Group, Primary extranodal and nodal non-Hodgkin's lymphoma. A survey of a population-based registry. European Journal of Cancer and Clinical Oncology. ,vol. 25, pp. 1203- 1210 ,(1989) , 10.1016/0277-5379(89)90416-1
R Liang, D Todd, T K Chan, E Chiu, A Lie, Y L Kwong, D Choy, F C Ho, Treatment outcome and prognostic factors for primary nasal lymphoma. Journal of Clinical Oncology. ,vol. 13, pp. 666- 670 ,(1995) , 10.1200/JCO.1995.13.3.666
M. S. Quraishi, E. M. Bessell, D. Clark, N. S. Jones, P. J. Bradley, Non-Hodgkin's lymphoma of the sinonasal tract. Laryngoscope. ,vol. 110, pp. 1489- 1492 ,(2000) , 10.1097/00005537-200009000-00015
Judith A. Ferry, Jeffrey Sklar, Lawrence R. Zukerberg, Nancy L. Harris, Nasal lymphoma. A clinicopathologic study with immunophenotypic and genotypic analysis. The American Journal of Surgical Pathology. ,vol. 15, pp. 268- 279 ,(1991) , 10.1097/00000478-199103000-00007
M. Shindoh, T. Takami, M. Arisue, T. Yamashita, T. Saito, T. Kohgo, K. Notani, Y. Totsuka, A. Amemiya, Comparison between submucosal (extra-nodal) and nodal non-Hodgkin's lymphoma (NHL) in the oral and maxillofacial region Journal of Oral Pathology & Medicine. ,vol. 26, pp. 283- 289 ,(1997) , 10.1111/J.1600-0714.1997.TB01238.X
Eppo B. Wolvius, Paul van der Valk, Jacqueline E. van der Wal, Paul J. van Diest, Peter C. Huijgens, Isaäc van der Waal, Gordon B. Snow, Primary extranodal non-Hodgkin lymphoma of the oral cavity. An analysis of 34 cases. European Journal of Cancer. Part B: Oral Oncology. ,vol. 30, pp. 121- 125 ,(1994) , 10.1016/0964-1955(94)90063-9
Anna-Lisa Söderholm, Christian Lindqvist, Kristiina Heikinheimo, Kai Forssell, Risto-Pekka Happonen, Non-Hodgkin's lymphomas presenting through oral symptoms. International Journal of Oral and Maxillofacial Surgery. ,vol. 19, pp. 131- 134 ,(1990) , 10.1016/S0901-5027(05)80126-2
Philippe Gaulard, Tawfiq Henni, Jean-Pierre Marolleau, Corinne Haioun, Zoubida Henni, Marie-Catherine Visin, Marine Divine, Michel Goossens, Jean-Pierre Farcet, Felix Reyes, Presence of HTLV‐I proviral DNA in patients with adult T‐Cell leukemia/lymphoma in Taiwan Cancer. ,vol. 62, pp. 705- 710 ,(1988) , 10.1002/1097-0142(19880815)62:4<705::AID-CNCR2820620410>3.0.CO;2-Z