Drug therapy during labor and delivery, part 2

摘要: Purpose. The drug therapy of common conditions and complications during labor delivery the fetal neonatal effects this are examined. Summary. pharmacologic that occur in primarily involves oxytocin prostaglandins for cervical ripening induction systemic regional narcotic analgesics pain. Because most medications used women do not have Food Drug Administration-approved labeling, pharmacists should understand benefits limitations mother. Although augmentation control pain often require therapy, other, less frequent, may labor. therapies these include anti-infective agents to treat maternal infection prevent diseases; antiretrovirals reduce perinatal HIV-1 transmission from mother fetus; corticosteroids lung immaturity; antihypertensives preeclampsia; anticonvulsants eclampsia; antibiotics prolong pregnancy improve outcomes after premature rupture membranes; tocolytics labor; oxytocin, ergot alkaloids, prostaglandin analogues postpartum hemorrhage. usually benign, but significant morbidity mortality involving mother, fetus, newborn ever-present risks. Conclusion. Awareness requiring will allow hospital make knowledgeable decisions about rapid accessibility critical unit.