Racial differences in the distribution of bladder cancer metastases: a population-based analysis.

摘要: Introduction Bladder cancer is the second most common genitourinary malignancy in United States. The incidence of bladder rises with age, and it two times more Caucasians than African-Americans (23.1 vs. 12.6 cases/100,000 persons). We aimed to investigate racial age-related differences distribution metastasis a large, contemporary cohort metastatic patients. Material methods Within National Inpatient Sample database (2008-2015) we identified 5,767 patients cancer. Trend test, Chi-square test multivariable logistic regression models were used evaluate relationship between ethnicity, site metastasis. Results Of cancer, 598 (10.4%) African-American. Lung was (28.6%) bone (21.7%). Overall, showed higher rates lung (+10.2%), liver (+7.5%) (+5.2%) metastases, compared (all p <0.01). Brain metastases rare both ethnicities (3.3 2.4%; = 0.2). Rates exclusive bone, or increased but African-Americans, regardless age strata. In models, African-American ethnicity independently predicted risk (Odds ratio: 1.69), (odds 1.50) 1.27) relative Caucasians. Moreover, dose-response effect found after combining three main factors for developing namely younger male gender. Conclusions Racial exist based on patients, imaging may be warranted this patient population, especially presence other gender age.