Extraction Techniques Leveraging Elevated Temperature and Pressure

摘要: This chapter introduces, explains, and evaluates several important sample preparation techniques available for pharmaceutical applications. In-depth discussion of Pressurized Fluid Extraction (also known as Liquid Extraction, or Accelerated Solvent Extraction), Microwave Assisted Supercritical is presented. The principles each technique, including instrumentation, method development, key parameters, advantages/limitations, are detailed. A number applications case studies described to illustrate technique in practice. Hot Water also summarized a member this extraction group. While unique, with its own pros cons respect applications, none provide universal solution preparation. Failure evaluate these part an analytical toolbox, however, can lead missing very simple difficult issues.