Changes in the Electrical Activity of the Olfactory Cortex Induced by Radiation and Drugs

作者: P. S. Timiras , D. E. Woolley , A. J. Silva , B. Williams

DOI: 10.2307/3572065

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摘要: of reserpine, pentobarbital, or pentylenetetrazol. In the prepyriform cortex, evoked potential elicited by stimulation lateral olfactory tract resembles a sinusoidal oscillation, and spontaneous electrical activity is dominated fast, waves. X-irradiation increased amplitude during first postirradiation week again one month after irradiation, shortened latency between stimulus response mainly reducing synaptic delay. general, effects 500 R were either greater lasted longer than those 250 R. These observations are interpreted to mean that in doses used has an excitatory effect on this interpretation supported neuropharmacological data. Reserpine administration nonirradiated rats decreased amplitude, but same drug irradiation. Pentobarbital reduced number waves activity, whereas subconvulsant dose pentylenetetrazol these oscillations.

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