A novel fusion of TPR and ALK in lung adenocarcinoma.

作者: Yoon-La Choi , Maruja E. Lira , Mineui Hong , Ryong Nam Kim , So-Jung Choi

DOI: 10.1097/JTO.0000000000000093

关键词:

摘要: … During screening for ALK fusions in 533 lung … elevated ALK 3’ expression but low scores for known ALK fusion variants. These results indicated that the tumor might harbor a novel ALK …

参考文章(15)
I. Bongarzone, C. Lanzi, A. Greco, S. Pagliardini, G. Della Porta, M. A. Pierotti, TRK-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas. Oncogene. ,vol. 7, pp. 237- 242 ,(1992)
Kathryn Albers, Elaine Fuchs, The Molecular Biology of Intermediate Filament Proteins International Review of Cytology-a Survey of Cell Biology. ,vol. 134, pp. 243- 279 ,(1992) , 10.1016/S0074-7696(08)62030-6
Feng Li, Yong-Ping Zhai, Yu-Mei Tang, Li-Ping Wang, Pin-Jun Wan, Identification of a novel partner gene, TPR, fused to FGFR1 in 8p11 myeloproliferative syndrome. Genes, Chromosomes and Cancer. ,vol. 51, pp. 890- 897 ,(2012) , 10.1002/GCC.21973
Donald Macdonald, Andreas Reiter, Nicholas C.P. Cross, The 8p11 myeloproliferative syndrome: a distinct clinical entity caused by constitutive activation of FGFR1. Acta Haematologica. ,vol. 107, pp. 101- 107 ,(2002) , 10.1159/000046639
Peter L. Bangs, Cynthia A. Sparks, Paul R. Odgren, Edward G. Fey, Product of the oncogene‐activating gene Tpr is a phosphorylated protein of the nuclear pore complex Journal of Cellular Biochemistry. ,vol. 61, pp. 48- 60 ,(1996) , 10.1002/(SICI)1097-4644(19960401)61:1<48::AID-JCB7>3.0.CO;2-2
N. R. Soman, P. Correa, B. A. Ruiz, G. N. Wogan, THE TPR-MET ONCOGENIC REARRANGEMENT IS PRESENT AND EXPRESSED IN HUMAN GASTRIC CARCINOMA AND PRECURSOR LESIONS Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 4892- 4896 ,(1991) , 10.1073/PNAS.88.11.4892
Maruja E Lira, Tae Min Kim, Donghui Huang, Shibing Deng, Youngil Koh, Bogun Jang, Heounjeong Go, Se-Hoon Lee, Doo Hyun Chung, Woo Ho Kim, Eric FPM Schoenmakers, Yoon-La Choi, Keunchil Park, Jin Seok Ahn, Jong-Mu Sun, Myung-Ju Ahn, Dong-Wan Kim, Mao Mao, None, Multiplexed Gene Expression and Fusion Transcript Analysis to Detect ALK Fusions in Lung Cancer The Journal of Molecular Diagnostics. ,vol. 15, pp. 51- 61 ,(2013) , 10.1016/J.JMOLDX.2012.08.006
Jeffery L. Kutok, Jon C. Aster, Molecular Biology of Anaplastic Lymphoma Kinase–Positive Anaplastic Large-Cell Lymphoma Journal of Clinical Oncology. ,vol. 20, pp. 3691- 3702 ,(2002) , 10.1200/JCO.2002.12.033
J. H. Coyle, Y.-C. Bor, D. Rekosh, M.-L. Hammarskjold, The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway. RNA. ,vol. 17, pp. 1344- 1356 ,(2011) , 10.1261/RNA.2616111
Eunice L. Kwak, Yung-Jue Bang, D. Ross Camidge, Alice T. Shaw, Benjamin Solomon, Robert G. Maki, Sai-Hong I. Ou, Bruce J. Dezube, Pasi A. Jänne, Daniel B. Costa, Marileila Varella-Garcia, Woo-Ho Kim, Thomas J. Lynch, Panos Fidias, Hannah Stubbs, Jeffrey A. Engelman, Lecia V. Sequist, WeiWei Tan, Leena Gandhi, Mari Mino-Kenudson, Greg C. Wei, S. Martin Shreeve, Mark J. Ratain, Jeffrey Settleman, James G. Christensen, Daniel A. Haber, Keith Wilner, Ravi Salgia, Geoffrey I. Shapiro, Jeffrey W. Clark, A. John Iafrate, Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer The New England Journal of Medicine. ,vol. 363, pp. 1693- 1703 ,(2010) , 10.1056/NEJMOA1006448