A model of oxygen flux through contact lenses.

摘要: Purpose Although oxygen transmissibility has been a favored index to describe the physiologic performance of contact lenses, it maintained by some that flux through lens would be more useful guide. Here, model is described allows estimated under open and closed eye wearing conditions. Methods The equivalent potential (EOP) was used approximate concentration beneath lens. A logarithmic relation between corneal consumption this level substituted into Fick's Law provide mathematical model. Paired data EOP (Dk/t), from previous empiric derivation, were entered nonlinear regression analysis Results modelling procedure produces good fit selected data. maximum during wear 7.5 microL/cm2 x h, consistent with determinations. Error estimates increased 0 0.55 microL/cm2/h at Dk/t values 200 10(-9) Barrer/cm, respectively, for eye. Conclusion This study provides workable estimating lenses. Varying underlying tension minimal variation result. number clinical applications, such as demonstrating advantages highly transmissible lenses limits which increasing can alter environment.