Systemic inflammation disrupts the developmental program of white matter

作者: Géraldine Favrais , Yohan van de Looij , Bobbi Fleiss , Nelina Ramanantsoa , Philippe Bonnin

DOI: 10.1002/ANA.22489

关键词:

摘要: Perinatal inflammation is a major risk factor for neurological deficits in preterm infants. Several experimental studies have shown that systemic can alter the programming of developing brain. However, these do not offer detailed pathophysiological mechanisms, and they rely on relatively severe infectious or inflammatory stimuli most likely reflect levels observed many human The goal present study was to test hypothesis moderate sufficient white matter development.

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