Impact of a Eukaryotic Translation Initiation Factor 3a Polymorphism on Susceptibility to Gastric Cancer.
作者： Kuijie Liu , Zhendong Lei , Hongliang Yao , Sanlin Lei , Hua Zhao
DOI: 10.1159/000447741
关键词:
摘要: Objective: To investigate single nucleotide polymorphisms in the eukaryotic translation initiation factor 3a (eIF3a) gene and risk for gastric cancer within Chinese population. Subjects Methods: A total of 322 patients with were selected as patient group 340 non-gastric control using case-control method. Polymerase chain reaction-sequence-specific primer technology was leveraged to genotype rs77382849 polymorphism eIF3a gene. The demographic characteristics study population other exposures factors collected. Unconditional logistic regression analysis performed determine association between cancer. Results: higher frequency GG homozygote observed compared controls (63.98 vs. 54.41%, p Conclusion: An susceptibility these patients.
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