Vector Arthropods and Host Pain and Itch Responses

摘要: Itch and pain are danger signals that induce protective responses of scratching withdrawal from painful stimuli. distinct, yet related, sensations involving increasingly well-characterized receptors, mediators, peripheral central neuronal pathways. Cutaneous itch alerts to the presence a probing or feeding arthropod vector may behaviors remove offending arthropod. Saliva composition differs significantly among genera species arthropods. A diverse array inhibitors hemostasis, immunomodulators, molecules block found in saliva. Repeated induces host neutralize actions some saliva molecules. Vector arthropod–induced is linked grooming related reduction tick numbers; awareness vectors, particularly mosquitoes ticks; positive correlation exists between induced by vectors lower incidence vector-borne disease transmission.