Orbital aspergillosis in immunocompetent patients.

摘要: Purpose To describe clinical, ultrasonographic, radiological and histopathological features of orbital aspergillosis in immunocompetent patients. Methods Medical records immunocompetant individuals with between November 1995 2010 were reviewed. Results Thirty-five cases (27 males, 8 females) Mean age at presentation was 37.63 (8–73) years mean duration symptoms 12.03 (0.5–84) months. Proptosis (22.63%) mass lesion (13.37%) the commonest presenting complaints. Presenting visual acuity better than 6/9 21 (60%) no perception light 3 (8%). Ocular motility restriction noted 25 (71%). The clinical differential diagnosis non-specific inflammatory disease (NSOID) (10.29%) followed by malignancy (7.20%). CT showed infiltrative lesions bone destruction 22 (63%), contiguous paranasal sinus involvement (63%) intracranial extension 10 (29%). Diagnosis histopathology microbiological evaluation. Fungal cultures revealed Aspergillus flavus 30 (86%) fumigatus 5 (14%). Treatment included conservative medical management 18 (51%) surgical debulking 17 (49%). Average follow-up 37.6 (3–183) months, patient survival 33/35 (94%). Conclusions Though is commonly seen immunocompromised patients, it should be suspected young proptosis insidious onset infiltrating involving sinuses. Definitive achieved Systemic steroids avoided prior to definitive diagnosis. Prolonged systemic antifungal therapy an option additional provides good control improved survival.