Scaffolds and Biologic Additives for ACL Surgery

摘要: Most ligaments in our bodies have excellent healing capabilities, but the ACL is an exception. If poor capability of due to its local environment, appropriate modifications environment may allow heal better. Various tissue engineering approaches been studied help treat injuries. Autografts and allografts most successful; they are current gold standard treatment. Synthetic materials used past with unsatisfactory outcomes, recent advances understanding biology biomechanics lead effective graft future. The use biomaterials xenografts also under investigation. Cell seeding attractive approach because active cells that participate can be delivered surgical site. studies helped us uncover role growth factors ligament healing; platelet-rich plasma (PRP) one way deliver factors, combination PRP collagen scaffolds has yielded exciting results animal studies.