作者: Lawrence D. Frenkel
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摘要: Ceftriaxone treatment (50 to 80 mg/kg once daily) was given 201 children between 1 month and 18 years of age. There were serious bacterial infections, including epiglottitis, pneumonia, cellulitis, osteomyelitis, septic arthritis, pyelonephritis, sepsis, meningitis. The common pathogens responsible for pediatric infections isolated from these patients included Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, pneumoniae, Escherichia coli. overall clinic cure rate 94%. Ten clinically improved but not cured. two clinical failures. Bacteriologic failure occurred in six patients. bacteriologic 97%. Twenty (10%) experienced adverse effects; none required discontinuation therapy. efficacy, safety, spectrum, convenience ceftriaxone monotherapy make this antimicrobial agent a candidate the choice selected infections.