Prostate-specific antigen-based prostate cancer screening: Past and future.

作者: Arnout R Alberts , Ivo G Schoots , Monique J Roobol

DOI: 10.1111/IJU.12750

关键词:

摘要: Prostate-specific antigen-based prostate cancer screening remains a controversial topic. Up to now, there is worldwide consensus on the statement that harms of population-based screening, mainly as result overdiagnosis (the detection clinically insignificant tumors would have never caused any symptoms), outweigh benefits. However, opportunistic takes place wide scale. The European Randomized Study Screening for Prostate Cancer showed reduction in mortality through prostate-specific antigen based-screening. These data need be individualized order avoid those who cannot benefit and start will. For lacking more optimal approach, should only started after process shared decision-making. focus future research unnecessary testing by further better biomarkers value multiparametric magnetic resonance imaging, potentially combined already existing multivariate risk prediction models.

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