N6-methyladenosine (m6A) RNA modification in cancer stem cells.

Jianzhao Liu, Yanan Yue, Dali Han, Xiao Wang, Ye Fu, Liang Zhang, Guifang Jia, Miao Yu, Zhike Lu, Xin Deng, Qing Dai, Weizhong Chen, Chuan He, A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation Nature Chemical Biology. ,vol. 10, pp. 93- 95 ,(2014) , 10.1038/NCHEMBIO.1432

Vladimir Ratushny, Michael D. Gober, Ryan Hick, Todd W. Ridky, John T. Seykora, From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma Journal of Clinical Investigation. ,vol. 122, pp. 464- 472 ,(2012) , 10.1172/JCI57415

Xiao-Li Ping, Bao-Fa Sun, Lu Wang, Wen Xiao, Xin Yang, Wen-Jia Wang, Samir Adhikari, Yue Shi, Ying Lv, Yu-Sheng Chen, Xu Zhao, Ang Li, Ying Yang, Ujwal Dahal, Xiao-Min Lou, Xi Liu, Jun Huang, Wei-Ping Yuan, Xiao-Fan Zhu, Tao Cheng, Yong-Liang Zhao, Xinquan Wang, Jannie M Rendtlew Danielsen, Feng Liu, Yun-Gui Yang, Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase Cell Research. ,vol. 24, pp. 177- 189 ,(2014) , 10.1038/CR.2014.3

Sung-Hak Kim, Kaushal Joshi, Ravesanker Ezhilarasan, Toshia R. Myers, Jason Siu, Chunyu Gu, Mariko Nakano-Okuno, David Taylor, Mutsuko Minata, Erik P. Sulman, Jeongwu Lee, Krishna P.L. Bhat, Anna Elisabetta Salcini, Ichiro Nakano, EZH2 protects glioma stem cells from radiation-induced cell death in a MELK/FOXM1-dependent manner. Stem cell reports. ,vol. 4, pp. 226- 238 ,(2015) , 10.1016/J.STEMCR.2014.12.006

Wei Huang, Chu-Bo Qi, Song-Wei Lv, Min Xie, Yu-Qi Feng, Wei-Hua Huang, Bi-Feng Yuan, Determination of DNA and RNA Methylation in Circulating Tumor Cells by Mass Spectrometry. Analytical Chemistry. ,vol. 88, pp. 1378- 1384 ,(2016) , 10.1021/ACS.ANALCHEM.5B03962

Chau-To Kwok, Amy D. Marshall, John E. J. Rasko, Justin J. L. Wong, Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia. Journal of Hematology & Oncology. ,vol. 10, pp. 39- 39 ,(2017) , 10.1186/S13045-017-0410-6

Daniel Thomas, Ravindra Majeti, Biology and relevance of human acute myeloid leukemia stem cells. Blood. ,vol. 129, pp. 1577- 1585 ,(2017) , 10.1182/BLOOD-2016-10-696054

Sicong Zhang, Boxuan Simen Zhao, Aidong Zhou, Kangyu Lin, Shaoping Zheng, Zhike Lu, Yaohui Chen, Erik P Sulman, Keping Xie, Oliver Bögler, Sadhan Majumder, Chuan He, Suyun Huang, None, m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program. Cancer Cell. ,vol. 31, pp. 591- 606 ,(2017) , 10.1016/J.CCELL.2017.02.013

Qi Cui, Hailing Shi, Peng Ye, Li Li, Qiuhao Qu, Guoqiang Sun, Guihua Sun, Zhike Lu, Yue Huang, Cai-Guang Yang, Arthur D. Riggs, Chuan He, Yanhong Shi, m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell Reports. ,vol. 18, pp. 2622- 2634 ,(2017) , 10.1016/J.CELREP.2017.02.059

A Visvanathan, V Patil, A Arora, A S Hegde, A Arivazhagan, V Santosh, K Somasundaram, Essential role of METTL3-mediated m(6)A modification in glioma stem-like cells maintenance and radioresistance Oncogene. ,vol. 37, pp. 522- 533 ,(2018) , 10.1038/ONC.2017.351