The Effect of Erythropoietin on Hematopoietic Organs of the Polycythemic Mouse

作者: K. NAKAO , F. TAKAKU , S. FUJIOKA , S. SASSA

DOI: 10.1182/BLOOD.V27.4.537.537

关键词:

摘要: Abstract Increased RNA-P32/DNA-P32 ratio, iron incorporation and heme synthesis in spleens of polycythemic mice was demonstrated following an injection erythropoietin. These changes were correlated with the appearance erythroblasts. findings suggest intimate relation between RNA stem cell differentiation.

参考文章(5)
F.W.J. Teale, Cleavage of the haem-protein link by acid methylethylketone Biochimica et Biophysica Acta. ,vol. 35, pp. 543- 543 ,(1959) , 10.1016/0006-3002(59)90407-X
W. Fried, L. F. Plzak, L. O. Jacobson, E. Goldwasser, Studies on Erythropoiesis. III. Factors Controlling Erythropoietin Production Experimental Biology and Medicine. ,vol. 94, pp. 237- 241 ,(1957) , 10.3181/00379727-94-22910
G Rosen, M Ogur, The nucleic acids of plant tissues; the extraction and estimation of desoxypentose nucleic acid and pentose nucleic acid. Archives of Biochemistry and Biophysics. ,vol. 25, pp. 262- 276 ,(1950)
Filmanowicz E, Gurney Cw, Studies on erythropoiesis. XVI. Response to a single dose of erythropoietin in polycythemic mouse. Journal of Laboratory and Clinical Medicine. ,vol. 57, pp. 65- 72 ,(1961)