Survival and Neurologic Outcomes of Out-of-Hospital Cardiac Arrest Patients Who Were Transferred after Return of Spontaneous Circulation for Integrated Post-Cardiac Arrest Syndrome Care: The Another Feasibility of the Cardiac Arrest Center

摘要: It has been proven that safety and efficiency of out-of-hospital cardiac arrest (OHCA) patients is transported to specialized hospitals have the capability performing therapeutic hypothermia (TH). However, outcome who transferred after return spontaneous circulation (ROSC) not well evaluated. We conducted a retrospective observational study between January 2010 March 2012. There were primary outcomes as good neurofunctional status at 1 month secondary survivals Samsung Medical Center (SMC) group group. A total 91 enrolled this study. was no statistical difference neurologic both groups (38% vs. 40.6% SMC group, P=0.908). in survival 2 (66% 75.6% P=0.318). In univariate multivariate models, ROSC induction time had association with outcomes. The significant differences groups. This finding suggests possibility integrated post-cardiac care for OHCA are from other center. Graphical Abstract Keywords: Hypothermia Therapy, Heart Arrest, Cardiopulmonary Resuscitation INTRODUCTION Out-of-hospital remains common public health problem leading cause morbidity mortality (1). Systematic, can improve (2, 3). particular, recent studies demonstrated (TH) an important resuscitation therapy improves rate relieves unfavorable neurological survivors 4). Despite TH being emphasized, medical community slow adopt hospital environment (5, 6). may be due some barriers, such lack knowledge about TH, financial logistic barriers (6, 7). Thus, it difficult perform systematic including all hospitals. Furthermore, post reported (3, 8). well-established setting, among 8, 9). Therefore, suggested center could provide regional cardiac-arrest (9, 10, 11, 12, 13). Recently, distance did affect (10, 12). these focused on transport field hospital. evaluate well-organized (14). showed inter-hospital pre-transferred cooling differ directly visited center. delay initiation associated increased risk death. Despite potential benefit (14), prehospital widely used effective equipment, manpower, specific guidelines (15). Therefore, most resuscitated start their arrival (15). For reason, we hypothesized would delayed cooling, which produce poor compared patients. aim