Portable mass spectrometry for measurement of anaesthetic agents and methane in respiratory gases

作者: P.G. Turner , A. Dugdale , I.S. Young , S. Taylor

DOI: 10.1016/J.TVJL.2007.03.017

关键词:

摘要: Monitoring the composition of gases breathed by anaesthetised patients requires measurement methods with fast responses, high accuracy and good reliability. There is also an increasing demand for systems to be able monitor more than one target analyte simultaneously, but some gas analysers can sensitive presence methane in exhaled breath, consequently leading inaccurate measurements anaesthetic agent. This study investigated feasibility employing portable quadrupole mass spectrometry volatile agents (halothane, isoflurane sevoflurane), accumulation rebreathing systems, inspired carbon dioxide oxygen concentrations during equine anaesthesia a clinical setting. The were easily measurable was detectable. instrument had advantage over short wavelength infrared absorption because it could other respiratory simultaneously at extremely low concentrations, although further optimisation required.

参考文章(35)
Mullenax Ch, Leek Bf, Nold Mm, Stewart We, Lindahl Il, Dougherty Rw, Pulmonary absorption of eructated gas in ruminants. American Journal of Veterinary Research. ,vol. 23, pp. 205- ,(1962)
P.M. Taylor, Interference with the Datex Normac anaesthetic agent monitor for halothane in horses and sheep Journal of the Association of Veterinary Anaesthetists of Great Britain and Ireland. ,vol. 17, pp. 32- 34 ,(1990) , 10.1111/J.1467-2995.1990.TB00386.X
J A Perman, S Modler, A C Olson, Role of pH in production of hydrogen from carbohydrates by colonic bacterial flora. Studies in vivo and in vitro. Journal of Clinical Investigation. ,vol. 67, pp. 643- 650 ,(1981) , 10.1172/JCI110079
John H. Bond, Rolf R. Engel, Michael D. Levitt, Factors influencing pulmonary methane excretion in man. An indirect method of studying the in situ metabolism of the methane-producing colonic bacteria. Journal of Experimental Medicine. ,vol. 133, pp. 572- 588 ,(1971) , 10.1084/JEM.133.3.572
RJ Elliott-Martin, TT Mottram, JW Gardner, PJ Hobbs, PN Bartlett, Preliminary investigation of breath sampling as a monitor of health in dairy cattle Journal of Agricultural Engineering Research. ,vol. 67, pp. 267- 275 ,(1997) , 10.1006/JAER.1997.0168
GEORGES ROLLY, LINDA VERSICHELEN, Methane accumulation during closed-circuit anesthesia. Anesthesia & Analgesia. ,vol. 79, pp. 545- 547 ,(1994) , 10.1097/00132586-199502000-00029
S. Taylor, R. F. Tindall, R. R. A. Syms, Silicon based quadrupole mass spectrometry using microelectromechanical systems Journal of Vacuum Science & Technology B. ,vol. 19, pp. 557- 562 ,(2001) , 10.1116/1.1359172
Michael J Tisdale, Metabolic abnormalities in cachexia and anorexia Nutrition. ,vol. 16, pp. 1013- 1014 ,(2000) , 10.1016/S0899-9007(00)00409-3
Naoki SASAKI, Seiji HOBO, Toyohiko YOSHIHARA, Measurement for breath concentration of hydrogen and methane in horses. Journal of Veterinary Medical Science. ,vol. 61, pp. 1059- 1062 ,(1999) , 10.1292/JVMS.61.1059