Socioeconomic status and changing inequalities in colorectal cancer? A review of the associations with risk, treatment and outcome.

摘要: Background: Upcoming mass screening for colorectal cancer (CRC) makes a review of recent literature on the association with socioeconomic status (SES) relevant, because marked and contradictory associations risk, treatment outcome. Methods: The Pubmed database using MeSH terms 'Neoplasms' or 'Colorectal Neoplasms' 'Socioeconomic Factors' articles added between 1995 1st October 2009 led to 62 articles. Results: Low SES groups exhibited higher incidence compared high in US Canada (range risk ratio (RR) 1.0-1.5), but mostly lower Europe (RR 0.3-0.9). Treatment, survival mortality all showed less favourable results people status: Patients low received often (neo)adjuvant therapy ranging from 0.4 0.99), had worse rates (hazard (HR) 1.3-1.8) generally highest up 1.6 colon 3.1 rectal cancer. Conclusions: A quite consistent trend was observed favouring individuals those that still remains treatment, thus also mortality. We did not find evidence low/high gradients chosen outcome are decreasing. To meet increasing inequalities CRC make successful, participation rate needs be realised soon starting program.