The Molecular Neurobiology of Depression

作者: Richard C. Shelton

DOI: 10.1016/J.PSC.2006.12.005

关键词:

摘要: The molecular neurobiology of depression begins with the concept that depressive disorders represent a family related but distinct conditions. Different points vulnerability in brain may predispose person to disorders. Unraveling these complex causes lead novel treatments can be used targeted fashion.

参考文章(65)
Paul Greengard, Eric J. Nestler, Protein phosphorylation in the nervous system ,(1984)
Michael J. Meaney, Moshe Szyf, Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome. Dialogues in clinical neuroscience. ,vol. 7, pp. 103- 123 ,(2005)
Charles B. Nemeroff, Neurobiological consequences of childhood trauma. The Journal of Clinical Psychiatry. ,vol. 65, pp. 18- 28 ,(2004)
Edward C. Dempsey, Alexandra C. Newton, Daria Mochly-Rosen, Alan P. Fields, Mary E. Reyland, Paul A. Insel, Robert O. Messing, Protein kinase C isozymes and the regulation of diverse cell responses American Journal of Physiology-lung Cellular and Molecular Physiology. ,vol. 279, ,(2000) , 10.1152/AJPLUNG.2000.279.3.L429
Rudolf Jaenisch, Adrian Bird, Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals Nature Genetics. ,vol. 33, pp. 245- 254 ,(2003) , 10.1038/NG1089
Ghanshyam N Pandey, Yogesh Dwivedi, Jagadeesh SridharaRao, Xinguo Ren, Philip G Janicak, Rajiv Sharma, Protein Kinase C and Phospholipase C Activity and Expression of Their Specific Isozymes Is Decreased and Expression of MARCKS Is Increased in Platelets of Bipolar but Not in Unipolar Patients Neuropsychopharmacology. ,vol. 26, pp. 216- 228 ,(2002) , 10.1016/S0893-133X(01)00327-X
Charles F. Gillespie, Charles B. Nemeroff, Hypercortisolemia and depression. Psychosomatic Medicine. ,vol. 67, ,(2005) , 10.1097/01.PSY.0000163456.22154.D2
Yogesh Dwivedi, Robert R. Conley, Rosalinda C. Roberts, Carol A. Tamminga, Ghanshyam N. Pandey, [3H]cAMP Binding Sites and Protein Kinase A Activity in the Prefrontal Cortex of Suicide Victims American Journal of Psychiatry. ,vol. 159, pp. 66- 73 ,(2002) , 10.1176/APPI.AJP.159.1.66
K. K. Yamamoto, G. A. Gonzalez, W. H. Biggs, M. R. Montminy, Phosphorylation-induced binding and transcriptional efficacy of nuclear factor CREB. Nature. ,vol. 334, pp. 494- 498 ,(1988) , 10.1038/334494A0
P.V Nguyen, N.H Woo, REGULATION OF HIPPOCAMPAL SYNAPTIC PLASTICITY BY CYCLIC AMP-DEPENDENT PROTEIN KINASES Progress in Neurobiology. ,vol. 71, pp. 401- 437 ,(2003) , 10.1016/J.PNEUROBIO.2003.12.003