Expresión de Her2/neu en carcinoma gástrico en el área metropolitana de Bucaramanga en el periodo 2006 a 2009

摘要: Introduction: gastric cancer has become a public health problem in the world and Colombia is one of leading causes mortality. The oncoprotein Her/2 neu shown to be an independent bad prognostic factor with variable expression ranging from 8 - 91% been associated aggressive disease lesser response treatment. Aim: determinate frequency its carcinoma, also histopathologic correlation patients Bucaramanga Metropolitan Area during 2006 2009. Materials methods: we conducted observational cross-sectional study population 409 cases Population based Cancer Registry Area. information was collected clinical history paraffin blocks. immunochemistry made manual HERCEPTEST method. Scores 0 1 were interpretated as negative, score 2 equivocal 3 positive. samples that underwent fluorescence immunohistochemistry situ. Results: males predominated 243 cases, intestinal type more prevalent 230 positive 46 there no significant statistical association histopathological subtype or gender. Conclusions: 11.2% carcinomas Area, this finding consistent other reports, neither any significance (MED.UIS.2013;26(2):21-8).