New-onset diabetes mellitus after pediatric liver transplantation.

摘要: In the first five yr after liver transplant, approximately one in 10 pediatric recipients will develop NODAT. Factors associated with higher risk for NODAT have been difficult to identify due lack of uniformity reporting and data collection. Limited studies reported those who are at an older age high-risk ethnic backgrounds, particular underlying conditions, such as CF primary sclerosing cholangitis. Immunosuppressive medications, including tacrolimus, cyclosporine A, GC, sirolimus, implicated contributing NODAT, varying degrees. Identifying highest risk, appropriately screening, diagnosing is critical initiating timely treatment avoiding potential complications. population, limited primarily insulin, some consideration metformin. Children should be monitored carefully complications DM, microalbuminuria, hypertension, hyperlipidemia, retinopathy.