Comparison of seven commercial kits for detection of antibodies to Borrelia burgdorferi.

摘要: Five enzyme immunoassay (EIA) and two Western blot (WB) commercial kits were compared for their ability to detect antibodies toBorrelia burgdorferi. The panel of 53 test sera consisted 25 positive burgdorferi, 15 negative such antibodies, 5 reactive in serologic tests syphilis, 8 containing antinuclear and/or rheumatoid factor. rate agreement with reference results was 93 %, 90 % 88 EIA from Diamedix, Cambridge Biotech, Mardx Sigma respectively. sensitivity specificity 84 100 respectively 76 94 68 83 Mardx, Sigma. three confirmatory tests, Biotech WB, General Biometrics P39 demonstrated 75 60 63 52 24 EIA, 44 WB. demonstrate the variable performance detection WB appears be a better than single protein EIA.