Metabolic pathways and pharmacokinetics of natural medicines with low permeability.
作者： Mei Zeng , Lan Yang , Dan He , Yao Li , Mingxin Shi
DOI: 10.1080/03602532.2017.1377222
关键词:
摘要: … Most natural medicines are the bioactive ingredients of traditional Chinese medicine. In contrast to synthetic chemical drugs, natural medicines are derived from nature such as plants, …
sci-hub.se 参考文章(86)
Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah, John R. Crison, A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability Pharmaceutical Research. ,vol. 12, pp. 413- 420 ,(1995) , 10.1023/A:1016212804288
Jing Wang, Shiping Ma, Tianhua Yan, Qiang Fu, UPLC-MS/MS determination of ephedrine, methylephedrine, amygdalin and glycyrrhizic acid in Beagle plasma and its application to a pharmacokinetic study after oral administration of Ma Huang Tang Drug Testing and Analysis. ,vol. 7, pp. 158- 163 ,(2015) , 10.1002/DTA.1635
Yun-Xia Li, Cheng Peng, Ruo-Qi Zhang, Xue Li, Xue-Hua Jiang, Pharmacokinetics of phillyrin and forsythiaside following iv administration to Beagle dog. European Journal of Drug Metabolism and Pharmacokinetics. ,vol. 34, pp. 79- 83 ,(2009) , 10.1007/BF03191155
Doo‐Man Oh, Rane L. Curl, Gordon L. Amidon, Estimating the fraction dose absorbed from suspensions of poorly soluble compounds in humans: a mathematical model. Pharmaceutical Research. ,vol. 10, pp. 264- 270 ,(1993) , 10.1023/A:1018947113238
Fang Yuan, Jie Chen, Wen-jin Wu, Su-zhen Chen, Xue-ding Wang, Zeng Su, Min Huang, Effects of matrine and oxymatrine on catalytic activity of cytochrome P450s in rats. Basic & Clinical Pharmacology & Toxicology. ,vol. 107, pp. 906- 913 ,(2010) , 10.1111/J.1742-7843.2010.00596.X
Chen, Yan, Hu, Gu, Chen, Gu, Chen, Chen, Improved pharmacokinetics and reduced toxicity of brucine after encapsulation into stealth liposomes: role of phosphatidylcholine. International Journal of Nanomedicine. ,vol. 7, pp. 3567- 3577 ,(2012) , 10.2147/IJN.S32860
Zhijie Zheng, Tongmeng Yan, Weiying Chen, Ling Ye, Lan Tang, Zhongqiu Liu, Pharmacokinetic determination of ephedrine in Herba Ephedrae and Wu Tou Tang decoctions in rats using ultra performance liquid chromatography tandem mass spectrometry. Xenobiotica. ,vol. 42, pp. 775- 783 ,(2012) , 10.3109/00498254.2012.658884
Chang Li, Zhi-Hong Yao, Zi-Fei Qin, Jin-Bo Zhang, Rui-Yuan Cao, Yi Dai, Xin-Sheng Yao, Isolation and identification of phase I metabolites of phillyrin in rats. Fitoterapia. ,vol. 97, pp. 92- 97 ,(2014) , 10.1016/J.FITOTE.2014.05.011
Shingo Oda, Tatsuki Fukami, Tsuyoshi Yokoi, Miki Nakajima, A comprehensive review of UDP-glucuronosyltransferase and esterases for drug development. Drug Metabolism and Pharmacokinetics. ,vol. 30, pp. 30- 51 ,(2015) , 10.1016/J.DMPK.2014.12.001
Min Li, Aixin Shi, Hongxian Pang, Wei Xue, Yang Li, Guoying Cao, Bei Yan, Fan Dong, Kexin Li, Wei Xiao, Guorong He, Guanhua Du, Xin Hu, Safety, tolerability, and pharmacokinetics of a single ascending dose of baicalein chewable tablets in healthy subjects. Journal of Ethnopharmacology. ,vol. 156, pp. 210- 215 ,(2014) , 10.1016/J.JEP.2014.08.031