Transition-metal-free reactions of boronic acids: 1,3-stereochemical induction in the substrate-controlled conjugate addition.
作者： Silvia Roscales , Víctor Ortega , Aurelio G. Csákÿ
DOI: 10.1021/JO402262M
关键词:
摘要: The substrate-controlled 1,3-stereoselective conjugate addition of boronic acids and potassium trifluoroborates under metal-free conditions has been developed. This reaction affords bicyclic acetals, which have used as key intermediates in the stereodivergent synthesis polysubstituted tetrahydropyrans.
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