Copper- or Phosphine-Catalyzed Reaction of Alkynes with Isocyanides. Regioselective Synthesis of Substituted Pyrroles Controlled by the Catalyst

作者: Shin Kamijo , Chikashi Kanazawa , Yoshinori Yamamoto

DOI: 10.1021/JA051875M

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摘要: … The copper-catalyzed reaction of isocyanides (CNCH 2 EWG 1 ) 1 with electron-deficient alkynes (RC≡CEWG 2 ) 2 gave the 2,4-di-EWG-substituted pyrroles 3 selectively… of substituted …

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