Optical fiber-based hybrid sers platform for in vivo detection of bio-molecules

作者: Ya-Hong Xie , Pu Wang

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摘要: An optical probe includes an fiber with a first end and second end, enhanced surface on portion of the fiber. The patterned base layer including multiple protruding nano-pyramids, intermediate over layer, graphene layer. Using to cover increases sensitivity surface-enhanced Raman spectroscopy (SERS) process performed in conjunction surface, further chemical stability bio-compatibility surface. Further, placing at provides self-contained for use SERS process, thereby allowing in-vivo characterization sample.

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