Time-to-update of systematic reviews relative to the availability of new evidence

摘要: A number of methods for deciding when a systematic review should be updated have been proposed, yet little is known about whether reviews are more quickly new evidence becomes available. Our aim was to examine the timing updates relative availability evidence. We performed retrospective analysis update published in Cochrane Database Systematic Reviews 2010 trial compared with and without signals defined by completion or publication studies that were included updates. found 43% (293/682) before June 2017, which 204 an primary outcome meta-analysis (median time 35.4 months; IQR 25.5–54.0), 38% (77/204) added trials, 4% (8/204) reported change conclusion. In 171 reconcilable reporting information, we did not find clear difference (p = 0.05) between 15 signal 25.3 months; 15.3–43.5) 156 34.4 months; 25.1–52.2). 145 (p = 0.33) 26.0 months; 19.3–49.5) 130 32.4 months; 24.1 46.0). minority 2017 incorporate from studies, very few led undertaken faster made New approaches finding early conclusion at risk may useful allocated resources updating reviews.