作者: Jason Z. Stoller , Jonathan A. Epstein
DOI: 10.1016/J.SEMCDB.2005.06.004
关键词:
摘要: Neural crest cells (NCCs) contribute to many organs and tissues during embryonic development. Amongst these, the cardiovascular system represents a fascinating example. In this review, recent advances in our understanding of developmental biology molecular genetics regulating cardiac NCC maturation will be summarized. While existence significant neural (NC) contribution developing heart has been appreciated for more than 20 years, only last few years have pathways process elucidated these mechanisms etiology congenital disease man become apparent. Emerging data suggest that ongoing studies reveal complex inductive interactions between NC series other cell types contributing system.