Molecular Evidence of Demographic Expansion of the Chagas Disease Vector Triatoma dimidiata (Hemiptera, Reduviidae, Triatominae) in Colombia

摘要: Background Triatoma dimidiata is one of the most significant vectors Chagas disease in Central America and Colombia, and, as species, its pattern genetic variation within among populations strongly affected by phylogeographic history. A putative origin from has been proposed for Colombian populations, high differentiation three biographically different population groups recently evidenced. Analyses based on putatively neutral markers provide data which past events, such expansions colonization, can be inferred. We analyzed genealogies nicotinamide adenine dinucleotide dehydrogenase 4 (ND4) cytochrome oxidase subunit 1-mitochondrial genes, well partial nuclear ITS-2 DNA sequences obtained across eco-geographical range to assess structure demographic factors that may explain geographical distribution T. this country. Results The results support a association between divergence location groups, suggesting clear signals expansion haplotypes groups. Additionally, empirical date estimation event suggests population's placed after emergence Panama Isthmus, it was possibly followed fragmentation process, perhaps resulting local adaptation accomplished orographic isolation. Conclusion Inferences about historical processes are generally accordance with have two important biotic events Great American Interchange uplift eastern Andes mountains central Colombia.