Factors associated with drug adherence and blood pressure control in patients with hypertension.

摘要: Study Objectives. To determine characteristics associated with drug adherence and blood pressure control among patients hypertension, to assess agreement between self-reported refill adherences. Design. Cross-sectional analysis of baseline data from an ongoing randomized controlled trial. Setting. Primary care center at urban, county health system in Indianapolis, Indiana. Patients. Four hundred ninety-two participants hypertension taking least one antihypertensive drug. Measurements Main Results. Social demographic factors, comorbidity, adherence, prescription systolic diastolic pressures were recorded baseline. Participants aged 57 ± 11 (mean SD) years, predominantly women (73%) African-American (68%), took 2.4 1.1 drugs. Agreement adherences was poor fair (κ = 0.21). On multiple logistic regression analysis, increased age (p≤0.002) being married (p=0.03) independent predictors improved whereas depressed had low (p=0.005), African-Americans (p<0.001). Compared nonadherent patients, adherent lower (-5.4 mm Hg by self-report −5.0 refill) (−2.7 −3.0 (p≤0.02). Increased the only other variable strongly both measures (p≤0.001). The association depression, race, sex model dependent. Conclusion. Age, sex, race depression are control. Self-reported appear provide complementary information reductions similar magnitude.