Investigation of vertical mandibular distraction osteogenesis on the masticatory muscles in a ’unilateral hemifacial microsomia like’ defect in the sheep model.

摘要: Distraction osteogenesis is a recently developed option for surgical correction of the craniofacial discrepancy but there are few studies that look at long-term effect relapse phenomenon. This study was conducted to bone and muscle response different consolidation remodelling periods. Thirty ten-week-old Merino lambs were subjected this current study. The surgically created defect performed on experimental side (right) by superficial masseter myectomy condylectomy. showed midline shift affected three months later. Marker screws placed both sides mandible examine adjustment vertical horizontal dimension mandible. In present study, left used as control. The corrected using ramus distraction protocol. latency period 7 days where device inactive. then 1 mm per day until distracted gap 10 radiograph. Initially, sheep divided into 8 groups later refined 6 statistical analysis; Group 1: Immediately post 2: Consolidation 2 month 3: 3 4: 5: 6: 4 months A ‘hemifacial microsomia like’ successfully it distraction. Cephalometric examination height significantly increased after completed. Examination structure in relation relapse. investigation radiological analysis, histological analysis direct measurement pre-distraction sacrifice well histomorphometric analysis. cephalometric distance between marker control sides. Bone histology investigated middle posterior position side. Quantiment software. responses adaptation measuring: weight medial pterygoid muscles; length points (4 landmarks); cross section thickness muscles ultrasound histopathological completion maturation period. formation shown continue longer A two-month insufficient time consolidate stable, evidenced during period. There no…