Chapter Three - The Family of Chalcone Synthase-Related Proteins: Functional Diversity and Evolution

摘要: Chalcone synthase (CHS), the prototype of family, appears to be ubiquitous in higher plants. It synthesizes precursor for biosynthesis thousands biologically important substances, and several these probably have interesting beneficial effects on human health. This chapter focuses advances understanding functions proteins this family. The members are basically defined by sequence similarity, thus assignment requires molecular characterization. However, there enzymes whose properties suggest that they belong feeding experiments more enzyme activities would nicely fit into Examples both included chapter. most exciting prospects, however, identification new finally rational design activities. recent first elucidation a CHS crystal structure provides clues such approaches.