Identification of the etiologies of chronic urticaria in children: A prospective study of 94 patients

摘要: Jirapongsananuruk O, Pongpreuksa S, Sangacharoenkit P, Visitsunthorn N, Vichyanond P. Identification of the etiologies chronic urticaria in children: A prospective study 94 patients. Pediatr Allergy Immunol 2010: 21: 508–514. © 2009 John Wiley & Sons A/S The (CU) childhood remains incompletely understood because limited data children. The objective this was to examine some possible CU children by focusing on functional autoantibody FceRIα and IgE, thyroid autoimmunity, urticarial vasculitis, parasitic infestation food allergy. Children 4–15 yr age with were investigated for complete blood count, erythrocyte sedimentation rate (ESR), antinuclear antibody (ANA), CH50, free-T4 (FT4), stimulating hormone (TSH), anti-thyroglobulin anti-microsomal antibody, autologous serum skin test (ASST), prick tests (SPT) foods, challenges, stool examination parasites. Ninety-four who met criteria recruited. Patients physical excluded. Eosinophilia elevated ESR found 23% 13%, respectively. High ANA titers 2%. None these patients had clinical features abnormal CH50 level, TSH FT4. Anti-thyroglobulin antibodies not detected. Positive ASST 38%. There no differences medication requirement remission between positive negative ASST. Parasites 5% without correlation. SPT foods 35%. challenges six/nine history allergy two/seven history. Food avoidance beneficial subgroup only.