Pathology of experimental chlamydiosis in chicks.

摘要: Twelve one-day-old chicks were experimentally inoculated with Chlamydia psittaci derived from turkeys. Acute chlamydial septicemic lesions induced by the inoculation into air sac and trachea. No produced esophageal injection. Clinically, affected showed emaciation mouth breathing, inactive while some birds died. Grossly, they had hepatomegaly, splenomegaly airsacculitis. Histopathologically, fibrinopurulent airsacculitis, pneumonia bronchitis, multiple fibrinous serositis in hepatic splenic capsules, peri- epicardium, mesenterium, focal endoarteritis aortae, activation of reticuloendothelial cells spleen, necrosis noted. Immunohistochemically, antigen granules present cytoplasm epithelial respiratory system, hepatocytes, macrophages sac, lung, serous membrane, liver, mesothelial various organs or tissues. Chlamydial multiplication tissues involved was preceded to form lesions.