Disparities in SARS-CoV-2 seroprevalence among individuals presenting for care in central North Carolina over a six-month period

摘要: Robust community-level SARS-CoV-2 prevalence estimates have been difficult to obtain in the American South and outside of major metropolitan areas. Furthermore, though some previous studies investigated association demographic factors such as race with exposure risk, fewer correlated risk surrogates for socioeconomic status health insurance coverage. We used a highly specific serological assay utilizing receptor binding domain spike-protein identify antibodies remnant blood samples collected by University North Carolina Health system. We estimated this cohort Bayesian regression, well critical higher odds. Between April 21st October 3rd 2020, total 9,624 unique were from clinical sites central NC we observed seroprevalence increase 2.9 (1.7, 4.3) 9.1 (7.2, 11.1) over study period. Individuals who identified Latinx associated highest odds ratio at 7.77 overall (5.20, 12.10). Increased also among Black individuals without public or private insurance. Our data suggests that care-accessing cohort, was significantly than cumulative cases reported geographical area six months into COVID-19 pandemic Carolina. The increased seropositivity ethnoracial grouping highlights urgent ongoing need address underlying social disparities these populations.