Overexpression of inhA, but not kasA, confers resistance to isoniazid and ethionamide in Mycobacterium smegmatis, M. bovis BCG and M. tuberculosis

作者: Michelle H. Larsen , Catherine Vilchèze , Laurent Kremer , Gurdyal S. Besra , Linda Parsons

DOI: 10.1046/J.1365-2958.2002.03162.X

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摘要: … tuberculosis H37Rv transformed with pMH29:: kasAB yielded a fivefold increased resistance to INH. Their overexpression plasmids differed from our plasmids with respect to the …

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