Antimicrobial stewardship programs in inpatient hospital settings: a systematic review.
作者： Brittin Wagner , Gregory A. Filice , Dimitri Drekonja , Nancy Greer , Roderick MacDonald
DOI: 10.1086/678057
关键词:
摘要: Objective. Evaluate the evidence for effects of inpatient antimicrobial stewardship programs (ASPs) on patient, prescribing, and microbial outcomes.Design. Systematic review.Methods. Search MEDLINE (2000 through November 2013), Cochrane Library, reference lists relevant studies. We included English language studies with patient populations to United States (ie, infectious conditions prescriptions required antimicrobials) that evaluated ASP interventions reported outcomes interest. Study characteristics data were extracted reviewed by investigators trained research personnel.Results. Few intervention types (eg, audit feedback, guideline implementation, decision support) substantially impacted outcomes, including mortality, length stay, readmission, or incidence Clostridium difficile infection. However, most not powered adequately demonstrate impacts outcomes. Most associated ...
jstor.org
researchgate.net 
sci-hub.se 参考文章(57)
J. C. McGregor, E. Weekes, G. N. Forrest, H. C. Standiford, E. N. Perencevich, J. P. Furuno, A. D. Harris, Impact of a computerized clinical decision support system on reducing inappropriate antimicrobial use: a randomized controlled trial. Journal of the American Medical Informatics Association. ,vol. 13, pp. 378- 384 ,(2006) , 10.1197/JAMIA.M2049
P. Lesprit, C. Landelle, C. Brun-Buisson, Clinical impact of unsolicited post-prescription antibiotic review in surgical and medical wards: a randomized controlled trial Clinical Microbiology and Infection. ,vol. 19, ,(2013) , 10.1111/1469-0691.12062
Peter Davey, Claire L Scott, Erwin Brown, Esmita Charani, Susan Michie, Craig R Ramsay, Charis A Marwick, interventions to improve antibiotic prescribing practices for hospital inpatients (updated protocol) Cochrane Database of Systematic Reviews. ,vol. 2017, ,(2017) , 10.1002/14651858.CD011236.PUB2
C. Pulcini, J. Dellamonica, G. Bernardin, N. Molinari, A. Sotto, Impact of an intervention designed to improve the documentation of the reassessment of antibiotic therapies in an intensive care unit Medecine Et Maladies Infectieuses. ,vol. 41, pp. 546- 552 ,(2011) , 10.1016/J.MEDMAL.2011.07.003
M Masia, C Matoses, S Padilla, A Murcia, V Sánchez, I Romero, A Navarro, I Hernández, F Gutiérrez, Limited efficacy of a nonrestricted intervention on antimicrobial prescription of commonly used antibiotics in the hospital setting: results of a randomized controlled trial European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 27, pp. 597- 605 ,(2008) , 10.1007/S10096-008-0482-X
Brad Spellberg, John G. Bartlett, David N. Gilbert, The Future of Antibiotics and Resistance New England Journal of Medicine. ,vol. 368, pp. 299- 302 ,(2013) , 10.1056/NEJMP1215093
Jean-Ralph Zahar, Christophe Rioux, Emmanuelle Girou, Anne Hulin, Colette Sauve, Alexandra Bernier-Combes, Christian Brun-Buisson, Philippe Lesprit, Inappropriate prescribing of aminoglycosides: risk factors and impact of an antibiotic control team Journal of Antimicrobial Chemotherapy. ,vol. 58, pp. 651- 656 ,(2006) , 10.1093/JAC/DKL288
Muhammad Mamdani, David McNeely, Gerald Evans, Janet Hux, Paul Oh, Natalie Forde, John Conly, Impact of a Fluoroquinolone Restriction Policy in an Elderly Population The American Journal of Medicine. ,vol. 120, pp. 893- 900 ,(2007) , 10.1016/J.AMJMED.2007.02.028
Douglas K. Owens, Kathleen N. Lohr, David Atkins, Jonathan R. Treadwell, James T. Reston, Eric B. Bass, Stephanie Chang, Mark Helfand, AHRQ Series Paper 5: Grading the strength of a body of evidence when comparing medical interventions—Agency for Healthcare Research and Quality and the Effective Health-Care Program Journal of Clinical Epidemiology. ,vol. 63, pp. 513- 523 ,(2010) , 10.1016/J.JCLINEPI.2009.03.009
J. Teo, A. L. H. Kwa, J. Loh, M. P. Chlebicki, W. Lee, The effect of a whole-system approach in an antimicrobial stewardship programme at the Singapore General Hospital European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 31, pp. 947- 955 ,(2012) , 10.1007/S10096-011-1391-Y