Genomics and the future of psychopharmacology: MicroRNAs offer novel therapeutics .
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DOI: 10.31887/DCNS.2019.21.2/DGURWITZ
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摘要: MicroRNAs (miRNAs) are short, noncoding RNAs functioning as regulators of the transcription protein-coding genes in eukaryotes. During last two decades, studies on miRNAs indicate that they have potential diagnostic and prognostic biomarkers for a wide range cancers. Research interest has moved to embrace further medical disciplines, including neuropsychiatric disorders, comparing miRNA expression mRNA targets between patient control blood samples postmortem brain tissues, well animal models disorders. This manuscript reviews recent findings implicated pathology mood schizophrenia, autism, their potential, tentative future therapeutics. The plausible contribution X chromosome larger prevalence major depression among women is also evaluated. .
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